2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
生物活性
Description
In Vivo
In Vitro
化合物的使用
Kinase Assay
Cell Assay
Animal Administration
参考文献
Terutroban is a thromboxane/prostaglandin endoperoxide receptor antagonist.
in vivo: Terutroban is a selective antagonist of the thromboxane/prostaglandin endoperoxide receptor, in preventing retinal ischaemia in a model of diabetes in rats. Terutroban significantly protect retinal vascularity from ischaemia in experimental diabetes, and this result could be attributed not only to its antiplatelet/antithrombotic activities but also to its vascular properties.Terutroban has antiplatelet properties. In addition, Terutroban has shown to improve flow-mediated dilatation of the brachial artery after a single administration in patients with coronary artery disease.Terutroban is a potent antithrombotic agent and also possesses antiatherosclerotic and antivasoconstrictor properties.
