2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
生物活性
Description
In Vivo
In Vitro
化合物的使用
Kinase Assay
Cell Assay
Animal Administration
参考文献
AG-1478 is an inhibitor of EGFR kinase with an IC50 value of 3 nM. It reversibly inhibits rat brain Kv1.5 potassium channels (IC50 = 9.8 µM) independent of PTK activity. AG-1478 also inhibits the growth of leiomyoma and myometrium cell cultures with IC50 values of 5.6 and 5.7 µM, respectively.3 This inhibitor suppresses MAP kinase activation and strongly inhibits induction of fos gene expression and DNA synthesis.
For the detailed information about the solubility of AG-1478 (Tyrphostin AG-1478) in water, the solubility of AG-1478 (Tyrphostin AG-1478) in DMSO, the solubility of AG-1478 (Tyrphostin AG-1478) in PBS buffer, the animal experiment（test） of AG-1478 (Tyrphostin AG-1478), the in vivo,in vitro and clinical trial test of AG-1478 (Tyrphostin AG-1478), the cell experiment（test） of AG-1478 (Tyrphostin AG-1478), the IC50, EC50 and Affinity of AG-1478 (Tyrphostin AG-1478) , please contact DC Chemicals.
