2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
生物活性
Description
In Vivo
In Vitro
化合物的使用
Kinase Assay
Cell Assay
Animal Administration
参考文献
Potent Ack1 and anaplastic lymphoma kinase (ALK) dual inhibitor (IC50 values are 4 and 12 nM respectively). Inhibits lung cancer H3122 cell proliferation (IC50 = 80 nM). Attenuates H3122 cell xenograft tumor growth in mice. Orally bioavailable. For the detailed information of KRCA-0008, the solubility of KRCA-0008 in water, the solubility of KRCA-0008 in DMSO, the solubility of KRCA-0008 in PBS buffer, the animal experiment (test) of KRCA-0008, the cell expriment (test) of KRCA-0008, the in vivo, in vitro and clinical trial test of KRCA-0008, the EC50, IC50,and affinity,of KRCA-0008, For the detailed information of KRCA-0008, the solubility of KRCA-0008 in water, the solubility of KRCA-0008 in DMSO, the solubility of KRCA-0008 in PBS buffer, the animal experiment (test) of KRCA-0008, the cell expriment (test) of KRCA-0008, the in vivo, in vitro and clinical trial test of KRCA-0008, the EC50, IC50,and affinity,of KRCA-0008, Please contact DC Chemicals.
