CCG-203971 产品说明书 Chemicals
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产品编号 DC10535
名称 CCG-203971

化学性质

CAS 1443437-74-8
分子式 C23H21CLN2O3
分子量 408.9
存储条件 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

生物活性

Description
In Vivo
In Vitro

化合物的使用

Kinase Assay
Cell Assay
Animal Administration

参考文献


CCG-203971 is an inhibitor of SRE activation in the prostate cancer cell line PC-3 (IC50 = 6.4 μM), with 87% inhibition of SRE activation achieved at 100 μM.2 This compound also inhibits PC-3 cell migration (IC50 = 4.2 μM), as determined by a scratch wound assay. CCG-203971 causes no cytotoxicity when evaluated by WST-1 assay.2 It is well tolerated in normal mice up to doses of 100 mg/kg given intraperitoneally over five days.
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