CB-839(Telaglenastat) 产品说明书 Chemicals
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产品编号 DC8042
名称 CB-839(Telaglenastat)

化学性质

CAS 1439399-58-2
分子式 C26H24F3N7O3S
分子量 571.1
存储条件 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

生物活性

Description
In Vivo
In Vitro

化合物的使用

Kinase Assay
Cell Assay
Animal Administration

参考文献


CB-839 is an investigational drug that works by inhibiting an enzyme involved in cancer metabolism called glutaminase. CB-839 has been shown to halt the growth of or kill cancer cells across a range of tumor types. The compound has demonstrated antitumor activity in several different tumor models in animals. In preclinical toxicology studies, CB-839 was well tolerated in animals at doses above those shown to inhibit tumor growth. CB-839 has also shown strong synergy with immunomodulatory agents and several kinase inhibitors that target growth factor pathways. For the detailed information of CB-839, the solubility of CB-839 in water, the solubility of CB-839 in DMSO, the solubility of CB-839 in PBS buffer, the animal experiment (test) of CB-839, the cell expriment (test) of CB-839, the in vivo, in vitro and clinical trial test of CB-839, the EC50, IC50,and affinity,of CB-839, For the detailed information of CB-839, the solubility of CB-839 in water, the solubility of CB-839 in DMSO, the solubility of CB-839 in PBS buffer, the animal experiment (test) of CB-839, the cell expriment (test) of CB-839, the in vivo, in vitro and clinical trial test of CB-839, the EC50, IC50,and affinity,of CB-839, Please contact DC Chemicals.
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