PRE-084 hydrochloride 产品说明书 Chemicals
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产品编号 DC8347
名称 PRE-084 hydrochloride

化学性质

CAS 138847-85-5
分子式 C19H27NO3.HCL
分子量 353.89
存储条件 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

生物活性

Description
In Vivo
In Vitro

化合物的使用

Kinase Assay
Cell Assay
Animal Administration

参考文献


High affinity, selective σ1 agonist (Ki values are 2.2 and 13091 nM for σ1 and σ2 receptors respectively). Selective over PCP receptors (IC50 > 100000 nM) and several other receptor systems. Produces antiamnesic and antitussive effects in vivo. Also exhibits protective effects in PC6.3 cells expressing mutant huntingtin by activating NF-κB signaling. For the detailed information of PRE-084 hydrochloride, the solubility of PRE-084 hydrochloride in water, the solubility of PRE-084 hydrochloride in DMSO, the solubility of PRE-084 hydrochloride in PBS buffer, the animal experiment (test) of PRE-084 hydrochloride, the cell expriment (test) of PRE-084 hydrochloride, the in vivo, in vitro and clinical trial test of PRE-084 hydrochloride, the EC50, IC50,and affinity,of PRE-084 hydrochloride, For the detailed information of PRE-084 hydrochloride, the solubility of PRE-084 hydrochloride in water, the solubility of PRE-084 hydrochloride in DMSO, the solubility of PRE-084 hydrochloride in PBS buffer, the animal experiment (test) of PRE-084 hydrochloride, the cell expriment (test) of PRE-084 hydrochloride, the in vivo, in vitro and clinical trial test of PRE-084 hydrochloride, the EC50, IC50,and affinity,of PRE-084 hydrochloride, Please contact DC Chemicals.
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