2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
生物活性
Description
In Vivo
In Vitro
化合物的使用
Kinase Assay
Cell Assay
Animal Administration
参考文献
G007-LK is a potent, "rule of 5" compliant and a metabolically stable TNKS1/2 inhibitor. G007-LK displayed high selectivity toward tankyrases 1 and 2 with biochemical IC50 values of 46 nM and 25 nM, respectively, and a cellular IC50 value of 50 nM combined with an excellent pharmacokinetic profile in mice. For the detailed information of G007-LK, the solubility of G007-LK in water, the solubility of G007-LK in DMSO, the solubility of G007-LK in PBS buffer, the animal experiment (test) of G007-LK, the cell expriment (test) of G007-LK, the in vivo, in vitro and clinical trial test of G007-LK, the EC50, IC50,and affinity,of G007-LK, For the detailed information of G007-LK, the solubility of G007-LK in water, the solubility of G007-LK in DMSO, the solubility of G007-LK in PBS buffer, the animal experiment (test) of G007-LK, the cell expriment (test) of G007-LK, the in vivo, in vitro and clinical trial test of G007-LK, the EC50, IC50,and affinity,of G007-LK, Please contact DC Chemicals.