2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
生物活性
Description
In Vivo
In Vitro
化合物的使用
Kinase Assay
Cell Assay
Animal Administration
参考文献
EW-7197 is a potent ALK5 inhibitor. EW-7197 showed potent in vivo anti-metastatic activity, indicating its potential for use as an anti-cancer therapy. EW-7197 inhibits TGF-β/Smad signaling. EW-7197 abrogates TGF-β1-induced tumor cell migration and invasion. EW-7197 inhibits breast cancer metastasis to the lung.EW-7197 prolongs the life span of BALB/c 4T1 mice via inhibition of EMT. EW-7197 inhibits metastasis and enhances the activity of cytotoxic T lymphocytes
(CTLs) in 4T1 orthotopic grafted mice. For the detailed information of EW-7197, the solubility of EW-7197 in water, the solubility of EW-7197 in DMSO, the solubility of EW-7197 in PBS buffer, the animal experiment (test) of EW-7197, the cell expriment (test) of EW-7197, the in vivo, in vitro and clinical trial test of EW-7197, the EC50, IC50,and affinity,of EW-7197, For the detailed information of EW-7197, the solubility of EW-7197 in water, the solubility of EW-7197 in DMSO, the solubility of EW-7197 in PBS buffer, the animal experiment (test) of EW-7197, the cell expriment (test) of EW-7197, the in vivo, in vitro and clinical trial test of EW-7197, the EC50, IC50,and affinity,of EW-7197, Please contact DC Chemicals.
