AZD2461 产品说明书 Chemicals
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产品编号 DC1037
名称 AZD2461

化学性质

CAS 1174043-16-3
分子式 C22H22FN3O3
分子量 395.43
存储条件 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

生物活性

Description
In Vivo
In Vitro

化合物的使用

Kinase Assay
Cell Assay
Animal Administration

参考文献


Description of AZD2461: AZD2461 is a novel and potent PARP inhibitor with lower affinity to P-glycoprotein. AZD2641 is currently in Phase I clinical study. The study is being conducted to see how it may work to treat solid tumors. The main purpose is to establish a safe dosage of the drug and provide additional information on any potential side effects this drug may cause. The study will also assess the blood levels and action of AZD2461 in the body over a period of time and will indicate whether the drug has a therapeutic effect on solid tumors. For the detailed information about the solubility of AZD2461 in water, the solubility of AZD2461 in DMSO, the solubility of AZD2461 in PBS buffer, the animal experiment(test) of AZD2461,the in vivo,in vitro and clinical trial test of AZD2461,the cell experiment(test) of AZD2461,the IC50, EC50 and Affinity of AZD2461, please contact DC Chemicals.
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