2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
生物活性
Description
In Vivo
In Vitro
化合物的使用
Kinase Assay
Cell Assay
Animal Administration
参考文献
GDC-0623 is a potent, ATP-uncompetitive inhibitors of MEK1(Ki=0.13 nM, +ATP); 6-fold weaker potency against HCT116 (KRAS(G13D), EC50=42 nM) versus A375 (BRAF(V600E), EC50=7 nM). For the detailed information of GDC-0623, the solubility of GDC-0623 in water, the solubility of GDC-0623 in DMSO, the solubility of GDC-0623 in PBS buffer, the animal experiment (test) of GDC-0623, the cell expriment (test) of GDC-0623, the in vivo, in vitro and clinical trial test of GDC-0623, the EC50, IC50,and affinity,of GDC-0623, Please contact DC Chemicals.
