化学性质
| CAS |
111011-63-3 |
 |
| 分子式 |
C34H38N3O7P |
| 分子量 |
631.6552 |
| 存储条件 |
2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
生物活性
| Description |
依福地平用途
Efonidipine(NZ-105)是T型和L型钙离子通道双重阻断剂。 |
| In Vivo |
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| In Vitro |
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化合物的使用
| Kinase Assay |
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| Cell Assay |
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| Animal Administration |
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参考文献
Efonidipine (NZ-105) is a potent, dual T-type and L-type calcium channel blocker, exhibits antihypertensive effect through vasodilatation; increases coronary blood flow by blocking L & T-type calcium channels and attenuates myocardial ischaemia, lowers blood pressure in cerebral resistance vessels and prevents hypertension induced brain damage; increases glomerular filtration rate without increasing intra-glomerular pressure and filtration fraction. |
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