SR3677 产品说明书 Chemicals
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产品编号 DC7246
名称 SR3677

化学性质

CAS 1072959-67-1
分子式 C22H24N4O4
分子量 408.45
存储条件 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

生物活性

Description
In Vivo
In Vitro

化合物的使用

Kinase Assay
Cell Assay
Animal Administration

参考文献


Potent and selective Rho-kinase inhibitor (IC50 values are 3 and 56 nM For ROCK-II and ROCK-I respectively).SR-3677 had an IC50 of ~3 nM in enzyme and cell based assays and had an off-target hit rate of 1.4% against 353 kinases, and inhibited only 3 out
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