PND-1186 产品说明书 Chemicals
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产品编号 DC7241
名称 PND-1186

化学性质

CAS 1061353-68-1
分子式 C25H26F3N5O3
分子量 501.5
存储条件 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

生物活性

Description
In Vivo
In Vitro

化合物的使用

Kinase Assay
Cell Assay
Animal Administration

参考文献


PND-1186, also known as SR-2156, is a potent FAK inhibitor with a 50% inhibitory concentration (IC50) of 1.5 nM in vitro. PND-1186 has an IC50 of ~100 nM in breast carcinoma cells. Notably, 1.0 µM PND-1186 (>5-fold above IC50) had limited effects on cell
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