2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
生物活性
Description
In Vivo
In Vitro
化合物的使用
Kinase Assay
Cell Assay
Animal Administration
参考文献
CAY10603 is a potent and selective inhibitor of HDAC6 with IC50 of 2 pM, as compared with 271, 252, 0.42, 6851, and 90.7 nM for HDAC1, 2, 3, 8, and 10, respectively.CAY10603 prevents the growth of several pancreatic cancer cell lines (IC50 = 0.1-1 μM). The HDAC6 inhibitor is more active in inhibiting cell growth than the broad spectrum HDAC inhibitor suberoylanilide hydroxamic acid (SAHA). For the detailed information of CAY10603, the solubility of CAY10603 in water, the solubility of CAY10603 in DMSO, the solubility of CAY10603 in PBS buffer, the animal experiment (test) of CAY10603, the cell expriment (test) of CAY10603, the in vivo, in vitro and clinical trial test of CAY10603, the EC50, IC50,and affinity,of CAY10603, Please contact DC Chemicals.
