CX-4945 (Silmitasertib) 产品说明书 Chemicals
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产品编号 DC7111
名称 CX-4945 (Silmitasertib)

化学性质

CAS 1009820-21-6
分子式 C19H12CLN3O2
分子量 349.77
存储条件 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

生物活性

Description
In Vivo
In Vitro

化合物的使用

Kinase Assay
Cell Assay
Animal Administration

参考文献


CX-4945 is selective For CK2, as it only inhibits 7 of the 238 kinases by more than 90% at concentration of 0.5 μM, which is 500-fold greater than the IC50 of CK2. Although in cell-free systems CX-4945 inhibits FLT3, PIM1, and CDK1 with IC50 of 35 nM, 46
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